factor xii deficiency การใช้

• Factor XII deficiency is a rare disorder that is inherited in an autosomal recessive manner.
• Since then, case studies and clinical studies identified an association between thrombosis and Factor XII deficiency.
• Unlike other clotting factor deficiencies, factor XII deficiency is totally asymptomatic and does not cause excess bleeding.
• As a result, the main concern related to factor XII deficiency is the unnecessary testing, delay in care, worry, etc . that may be prompted by the abnormal lab result.
• Factor XII does play an important role in clot formation during " in vitro " measurements of the partial thromboplastin time, which causes these measurements to be markedly prolonged in patients with factor XII deficiency, usually well beyond even what is seen in hemophilia A, hemophilia B, or factor XI deficiency.